AOSNP-ADAPTR

Adapting Diagnostic Approaches for Practical Taxonomy in Resource-Restrained Regions

Objectives

  • Build an optimal adaptation of the current WHO CNS5 classification, suitable for routine diagnostic practice in resource-restrained Asian-Oceanian settings.
  • Ultimately benefit all patients with CNS tumors worldwide, especially at centers with resource constraints.
AOSNP-ADAPTR Initiative
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Key Components of ADAPTR Recommendations

RL I

Histology only + special stains

RL II

+ Basic diagnostic IHC markers
(GFAP, S-100, Ki-67, EMA, CD34..)

RL III

+ Surrogate IHC molecular markers
( IDH1p.R132H, ATRX, H3p.K27M,
H3p.K27me3, L1CAM…)

RL IV

+ Basic molecular tests
(FISH, Sanger, PCR)

RL V

+ Advanced molecular tests
(NGS, DNA methylation profiling)

Resource levels (RLs) of diagnostic pathology services identified by ADAPTR (based on the diverse range of in house/ local resource availability)

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Research

AOSNP Adapter Team

Steering committee

Chair: 

Takashi Komori

Co-Chair:

Chitra Sarkar

Members:
Vani Santosh, Ho-Keung Ng, Michael Buckland, Maysa Al-Hussaini, Sung-Hye Park, Tarik Tihan

Advisory Board

International Neuropathology Advisors:

David N. Louis
Pieter Wesseling
Catriona McLean

Neuro-oncology Advisors:

Rakesh Jalali
Zarnie Lwin
Girish Chinnaswamy

Molecular Oncology Advisor:

Koichi Ichimura

Neurosurgery Advisors:

Yonehiro Kanemura

Neuroradiology Advisor:

Sona A. Pungavkar

Working Committees

Adult-type diffuse gliomas

Chair: Vani Santosh
Co-Chair: Ho-Keung Ng
Steering Member: Takashi Komori
Working Members: Shilpa Rao, Junji Shibahara, Hideaki Yokoo

Pediatric-type diffuse gliomas

Chair: Vani Santosh
Co-Chair: Sung-Hye Park
Steering Member: Tarik Tihan
Working Members: Se Hoon Kim, Yue-Shan Piao, Shilpa Rao

Circumscribed astrocytic glioma

Chair: Tarik Tihan
Co-Chair: Buckland M
Steering Member: Takashi Komori
Working Members: Sonika Dahiya, Se Hoon Kim, Yue-Shan Piao

Pediatric-type diffuse high-grade gliomas

Chair: Sung-Hye Park
Co-Chair: Maysa Al-Hussaini
Steering Member: Ho-Keung Ng
Working Members: Geeta Chacko, Sonika Dahiya, Shinya Tanaka

Ependymal Tumors

Chair: Michael Buckland
Co-Chair: Ho-Keung Ng
Steering Member: Vani Santosh
Working Members: Geeta Chacko, Kenta Masui, Junji Shibahara

Embryonal Tumors

Chair: Maysa Al-Hussaini
Co-Chair: Chitra Sarkar
Steering Member: Sung-Hye Park
Working Members: Yue-Shan Piao, Vaishali Suri, Hideaki Yokoo

General principles and diagnostic procedures

Chair: Takashi Komori
Co-Chair: Michael Buckland
Steering Member: Chitra Sarkar
Working Members: Kenta Masui, Vaishali Suri, Shinya Tanaka

The 20th International Congress of Neuropathology 2023 Berlin

Scientific session - Neurooncology

Session 23 - Neurooncology

AOSNP Guidelines for Adapting Diagnostic Approaches for Practical Taxonomy in Resource-Limited Regions (AOSNP-ADAPTR)

Appointment

  • 15/09/2023
  • 15:45 - 17:15
  • Bernhard von Langenbeck (1st floor) small auditorium, 90 seats

S23-NO-T1-5 Invited Talk

  • Introduction: Chitra Sarkar (New Delhi, IN)
  • Adult diffuse gliomas: Vani Santosh (Bengaluru, IN)
  • Pediatric diffuse and circumscribed gliomas: Takashi Komori (Tokyo, Japan)
  • Embryonal tumors: Maysa Al-Hussaini (Amman, JO)
  • Ependymomas: Michael Buckland (Sydney, AU)

AOSNP received official support from the International Society of Neuropathology (ISN), enabling it to host a symposium at the ISN Congress.